Research Associate

University of Manchester

Laboratory-based postdoctoral research in the Trost Lab to characterise bacterial phagosomes in macrophages using flow-cytometry-based isolation and state-of-the-art proteomics.

Manchester, United KingdomSchool of Biological Sciences, Division of Molecular and Cellular Function, Trost Lab£37,694 to £46,049 per annum depending on experience

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Employment

Vacancy terms

Career stage: Postdoctoral researcher
Employment type: Not stated
Contract: Not stated
Contract ends: Not stated
Original contract term: 24 months
Schedule: Full time, 1.0 FTE
Workplace: Not stated
FTE: Not stated
Salary: £37,694 to £46,049 per annum depending on experience
Department or school: School of Biological Sciences, Division of Molecular and Cellular Function, Trost Lab
Posted: Not stated

Role

Responsibilities

Isolate primary murine and bone-marrow-derived macrophages
Infect macrophages with Salmonella enterica Typhimurium
Isolate Salmonella vacuoles/phagosomes by flow cytometry
Prepare samples for proteomics
Use R analysis pipelines
Write research for publication
Support student and PhD projects

Candidate profile

Qualifications and requirements

Qualifications

Relevant PhD or equivalent, completed or near completion
Extensive hands-on experience infecting mammalian cells with bacterial pathogens
Strong core laboratory and bench skills
Ability to plan and progress research independently
At least one first-author publication in an internationally recognised journal or repository

Requirements

Extensive hands-on bacterial infection of mammalian cells and strong laboratory research experience.
Relevant PhD or equivalent. The advert seeks a post-doctoral scientist with background in infection biology, microbiology, molecular immunology, biochemistry or cell biology.
Mammalian cell infection
Primary murine macrophages
Bone-marrow-derived macrophages
Flow cytometry
Proteomics sample preparation
R data-analysis pipelines

Preferred qualifications

Experience with Salmonella and mutant generation
Flow cytometry experience
Macrophage experience
Large omics dataset analysis in R

Employment conditions

Full time, 1.0 FTE
24 months

Employment package

Benefits

£37,694 to £46,049 per annum depending on experience
Employer pension contribution, 29 days annual leave plus bank holidays and Christmas closure, ride-to-work and EV car schemes. Visa sponsorship is not stated.
Full time, 1.0 FTE
24 months

Application

Documents and steps

Documents

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Steps

Apply through the University of Manchester vacancy-specific JobTrain application gateway.

Official evidence

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